Comments on: Sour grapes http://www.politigenomics.com/2009/08/sour-grapes.html Politics, Information Technology, and Genomics Mon, 31 Oct 2011 00:27:27 +0000 hourly 1 http://wordpress.org/?v=3.2.1 By: H. Hare http://www.politigenomics.com/2009/08/sour-grapes.html/comment-page-1#comment-15334 H. Hare Tue, 18 Aug 2009 14:48:03 +0000 http://www.politigenomics.com/?p=1425#comment-15334 SOLiD proof that Solexa won ? SOLiD proof that Solexa won ?

]]> By: Basics: Sequencing DNA, Part 2 « Genetic Inference http://www.politigenomics.com/2009/08/sour-grapes.html/comment-page-1#comment-15325 Basics: Sequencing DNA, Part 2 « Genetic Inference Thu, 13 Aug 2009 11:19:00 +0000 http://www.politigenomics.com/?p=1425#comment-15325 [...] Second generation sequencing techniques overcome this restriction, by finding ways to sequence the DNA without having to move it around. You stick the bit of DNA you want to sequence in a little dot, called a cluster, and you do the sequencing there; as a result, you can pack many millions of clusters into one machine. Sequencing a strand of DNA while keeping it held in place is tricky, and requires a lot of cleverness. I am only going to talk in detail about Illumina’s reversible termination sequencing, partly because it is the most similar to Sanger sequencing, but mostly because I too am part of the shadowy cabal of people trying to destroy ABI. [...] [...] Second generation sequencing techniques overcome this restriction, by finding ways to sequence the DNA without having to move it around. You stick the bit of DNA you want to sequence in a little dot, called a cluster, and you do the sequencing there; as a result, you can pack many millions of clusters into one machine. Sequencing a strand of DNA while keeping it held in place is tricky, and requires a lot of cleverness. I am only going to talk in detail about Illumina’s reversible termination sequencing, partly because it is the most similar to Sanger sequencing, but mostly because I too am part of the shadowy cabal of people trying to destroy ABI. [...]

]]> By: dd http://www.politigenomics.com/2009/08/sour-grapes.html/comment-page-1#comment-15318 dd Wed, 12 Aug 2009 13:15:54 +0000 http://www.politigenomics.com/?p=1425#comment-15318 Chris, I never said that UK's politics weren't interesting. Rather I said that the US is <strong>not</strong> the only place with with interesting politics. UK, Italy, Russia, Iran, Iraq, Afghanistan, and Pakistan, all "interesting". Chris, I never said that UK’s politics weren’t interesting. Rather I said that the US is not the only place with with interesting politics. UK, Italy, Russia, Iran, Iraq, Afghanistan, and Pakistan, all “interesting”.

]]> By: Chris Jones http://www.politigenomics.com/2009/08/sour-grapes.html/comment-page-1#comment-15316 Chris Jones Wed, 12 Aug 2009 11:55:41 +0000 http://www.politigenomics.com/?p=1425#comment-15316 Thanks for digging that out for us - what a fun read! But the most surprising thing for me is that you thought UK's politigenomics might not be interesting! The House of Lords is as mad as a box of frogs. Combine that with a few eccentric, geeky English men in white coats and....... Thanks for digging that out for us – what a fun read!

But the most surprising thing for me is that you thought UK’s politigenomics might not be interesting! The House of Lords is as mad as a box of frogs. Combine that with a few eccentric, geeky English men in white coats and…….

]]> By: Joey Bedell http://www.politigenomics.com/2009/08/sour-grapes.html/comment-page-1#comment-15313 Joey Bedell Tue, 11 Aug 2009 21:04:05 +0000 http://www.politigenomics.com/?p=1425#comment-15313 An amazing find of the letter written to the House of Lords. Very interesting reading both here and on Nick's site. An amazing find of the letter written to the House of Lords. Very interesting reading both here and on Nick’s site.

]]> By: Pathogens: Genes and Genomes » ABI challenge Sanger Centre’s decision to return their instruments http://www.politigenomics.com/2009/08/sour-grapes.html/comment-page-1#comment-15312 Pathogens: Genes and Genomes » ABI challenge Sanger Centre’s decision to return their instruments Tue, 11 Aug 2009 11:16:56 +0000 http://www.politigenomics.com/?p=1425#comment-15312 [...] David Dooling has uncovered an intriguing letter from Kevin McKernan, Senior Director of Scientific Operations at ABI sent to the House of Lords last November. The letter concerns the Sanger Centre’s decision to return their five ABI SoLiD instruments in order to concentrate on building Illumina (Solexa) capacity. This was of course a big blow to ABI – the Sanger Centre is Europe’s largest sequencing facility. [...] [...] David Dooling has uncovered an intriguing letter from Kevin McKernan, Senior Director of Scientific Operations at ABI sent to the House of Lords last November. The letter concerns the Sanger Centre’s decision to return their five ABI SoLiD instruments in order to concentrate on building Illumina (Solexa) capacity. This was of course a big blow to ABI – the Sanger Centre is Europe’s largest sequencing facility. [...]

]]> By: Nick Loman http://www.politigenomics.com/2009/08/sour-grapes.html/comment-page-1#comment-15311 Nick Loman Tue, 11 Aug 2009 11:12:56 +0000 http://www.politigenomics.com/?p=1425#comment-15311 Interesting find David! I have posted some thoughts on the matter here: http://pathogenomics.bham.ac.uk/blog/2009/08/abi-challenge-sanger-centre/ Interesting find David! I have posted some thoughts on the matter here: http://pathogenomics.bham.ac.uk/blog/2009/08/abi-challenge-sanger-centre/

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