We recently published a paper in BMC Bioinformatics describing the laboratory information management system (LIMS) we have implemented at The Genome Center at Washington University. The title of the paper is Design and implementation of a generalized laboratory data model. BMC Bioinformatics is an open-access journal, so the paper is release under a Creative Commons license. A lot of the challenges we faced (and still face) in developing the LIMS are widely applicable in software engineering. For example, making a system that was both very flexible and very scalable is quite challenging. The flexibility is needed because, as a research facility, our pipelines are constantly changing. Scalability is important because, as a genome sequencing center, we have very high data throughput (tens of millions of transactions per month).