PolITiGenomics


Politics, Information Technology, and Genomics

Second whole cancer genome published

Today in the New England Journal of Medicine the second paper detailing the whole genome sequencing of a tumor and its matched normal was published: Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome. Accompanying the article is an editorial well worth reading by Jim Downing from St. Jude Children's Research Hospital discussing the significance of these whole genome sequence efforts from the medical researcher and practitioner's perspective. Dan Koboldt has posted a nice... Full Post


SNP vs. SNP

At the NHGRI Sequencing Advisory Panel meeting last week, there was some confusion about how we use SNP array data and dbSNP in the DNA sequencing world. SNP arrays are, when you boil it down, a quick and cheap way to sequence, i.e., determine the nucleotide at, specific DNA positions in the genome. For each sample to be sequenced at The Genome Center, we use SNP array data from that sample to measure breadth of... Full Post


HMP Short Attention Span Theater

For those of you who don't like reading, The Genome Center's George Weinstock, Ph.D., explains the Human Microbiome Project and a few of the HMP demonstration project grants in under two and a half minutes. Full Post


Download sequence data fast

More and more data are being submitted to the NCBI Short Read Archive (SRA). So you may ask yourself, "How am I going to download all that data?" Well, as luck would have it, you can download it using the same high-speed network protocol that we use to upload it, Aspera. You can download the Aspera Connect browser plugin (it is offered at not cost, but sadly is not free), install it, and then begin... Full Post


Celebrity Waitress & Waiters Night

The St. Louis Crisis Nursery will be hosting their annual Celebrity Waitress and Waiters Night on August 20, 2009 at Canyon Café and Cardwell’s at the Plaza, both located in Plaza Frontenac. St. Louis celebrities and politicians will be waiting on tables and all tips received will be donated to the Crisis Nursery. This is a popular event, so be sure to make your reservations soon. Full Post