PolITiGenomics

Next-Generation Sequencing Informatics

Thursday, December 4th, 2008 Posted in IT, genomics | 2 Comments »

I have put together a table with a bunch of important metrics for the major next-generation sequencing platforms: Next-Generation Sequencing Informatics (there is also a link on the left-hand side ... Read more..

Personal DNA testing

Wednesday, July 9th, 2008 Posted in genomics | No Comments »

Last night on NOVA scienceNOW there was a segment on the personal DNA tests currently being marketed to consumers (you can watch the segment on the website, unfortunately no ability ... Read more..

What’s in an SRF?

Monday, June 30th, 2008 Posted in genomics | No Comments »

I have written a bit about the NCBI Short Read Archive (SRA), its internals, and data transfer rates. Here is some information about the data format people are using to ... Read more..

How much?

Friday, June 20th, 2008 Posted in genomics | No Comments »

The Genome Center recently published a paper entitled Aspects of coverage in medical DNA sequencing that develops a model for diploid sequence coverage using data from massively parallel sequencing platforms ... Read more..

454 XLR-HD

Thursday, June 12th, 2008 Posted in IT, genomics | 8 Comments »

The next upgrade of the 454 FLX platform is called Titanium. The previous name gave a better indication of what the upgrade entails: XLR-HD which is short for eXtra ... Read more..

N Genomes

Friday, May 9th, 2008 Posted in genomics | 5 Comments »

Earlier this week there were several meetings about the 1000 Genomes Project at Cold Spring Harbor Labs. The first meeting Monday morning was about data flow and data repositories. ... Read more..

Mass genomics

Monday, March 31st, 2008 Posted in genomics | No Comments »

A colleague of mine in our human analysis group, Dan Koboldt, has started a blog called Mass Genomics. His first blog post is about his efforts to develop methodologies ... Read more..

1000 Genomes

Monday, March 17th, 2008 Posted in genomics | 2 Comments »

This week The Genome Center will begin sequencing our first samples from the 1000 Genomes Project. This project, which aims to create a much deeper understanding of normal human ... Read more..

The Genome Age or, A Young Genomicist’s Illustrated Primer

Friday, February 22nd, 2008 Posted in genomics | 1 Comment »

If you are interested in learning more about the next-generation sequencing technologies, i.e., 454, Solexa (Illumina), and AB SOLiD, you can get a quick overview from a recent article by ... Read more..

454 Informatics

Friday, January 18th, 2008 Posted in IT, genomics | 1 Comment »

I recently received this request. We've taken on 454 sequencing and would like information about the amount and type of bioinformatics support needed to help investigators with their data. Our ... Read more..